DKK-1, Rat (HEK293, His, solution)

DKK-1 Protein, with co-receptor and lipoprotein receptor binding activities, crucially regulates ossification and neuron death positively. Primarily located in the extracellular space, DKK-1 is implicated in anodontia, showing biased expression in kidney (RPKM 4.7), brain (RPKM 0.6), and two other tissues. Its role in the WNT signaling pathway and impact on visual epilepsy highlight its significance in developmental and neurological contexts. DKK-1 Protein, Rat (HEK293, His, solution) is the recombinant rat-derived DKK-1 protein, expressed by HEK293 , with C-His labeled tag.

MTVVRAVAAV RFLVVLSTMA LCSLPPLGVS ATLNSVLINS NAIKNLPPPL GGAGGQPGSA VSVAPGVLYE GGNKYQTLDN YQPYPCAEDE ECGTDEYCSS PSRGAAGVGG VQICLACRKR RKRCMRHAMC CPGNYCKNGI CMPSDHSHLP RGEIEEGIIE NLGNDHGAGD GYPRRTTLTS KIYHTKGQEG SVCLRSSDCA TGLCCARHFW SKICKPVLKE GQVCTKHRRK GSHGLEIFQR CYCGEGLACR IQKDHHQTSN SSRLHTCQRH