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PD 158771

Product Specifications

UNSPSC Description

PD 158771 is an antipsychotic agent that functions as a partial agonist for D2 /D3 receptors (Ki = 42.0/13.7 nM) and as an agonist for 5-HT1A receptors (Ki = 2.6 nM). PD 158771 can be utilized in antipsychotic research[1].

Target Antigen

5-HT Receptor; Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pd-158771.html

Smiles

C1(N[C@H]2CC[C@H](CCN3CCN(C4=CC=CC=C4)CC3)CC2)=NC=CC=N1

Molecular Weight

365.52

References & Citations

[1]Akunne HC, et al. PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects. Neuropharmacology. 2000 Apr 27;39(7):1197-210.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-167648/PD-158771-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-167648/

Clinical Information

No Development Reported

CAS Number

189152-50-9

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