Ethoxysanguinarine
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A) . Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1].
Product Specifications
CAS Number
28342-31-6
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ethoxysanguinarine.html
Purity
98.81
Solubility
DMSO : 60 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
CN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C6=C(OCO6)C=C5)C1OCC
Molecular Formula
C22H19NO5
Molecular Weight
377.39
References & Citations
[1]Jin L, et al. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A. Int J Oncol. 2018 Mar 16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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