What is the catalog number for 2',3'-cGAMP?

The catalog number for 2',3'-cGAMP is orb3029215.

What sizes are available for 2',3'-cGAMP?

2',3'-cGAMP is available in the following size(s): 1 mg.

Is 2',3'-cGAMP in stock?

2',3'-cGAMP is currently made to order / not held in immediate stock. Contact us for lead time.

2',3'-cGAMP

2',3'-cGAMP is an endogenous cyclic dinucleotide (CDN) produced by cGAS (cGAMP synthase) in response to double-stranded DNA in the cytoplasm. It acts as a STING activator and ligand, inducing interferons (IFNs) via the TBK1/IRF3 pathway and pro-inflammatory factors via the NF-κB pathway.

Product Specifications

CAS Number

1441190-66-4

Product Name Alternative

Cyclic GMP-AMP, 2'-3'-Cyclic GMP-AMP, 2',3' cGAMP, 2',3'cGAMP, 2',3'-cGAMP, Human Endogenous Metabolite

Field of Research

Immunology & Inflammation, Metabolism Research, Neuroscience

Purity

98.65% (May vary between batches)

Solubility

H2O:≥ 40 mg/mL

Smiles

O[C@H]1[C@@]2 ([C@@H] (O[C@]1 (COP (=O) (O) O[C@@]3 ([C@@] (COP (=O) (O) O2) (O[C@H] ([C@@H]3O) N4C=5C (N=C4) =C (N) N=CN5) [H]) [H]) [H]) N6C7=C (N=C6) C (=O) N=C (N) N7) [H]