Halofantrine hydrochloride
Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.
Product Specifications
CAS Number
36167-63-2
Product Name Alternative
Malaria, Halofantrine Hydrochloride, Halofantrine hydrochloride, SKF 102886, SKF102886, SKF-102886, WR 171669, WR171669, WR-171669, WR-171669 hydrochloride
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (3.73 mM) ; DMSO:24 mg/mL (44.7 mM)
Smiles
Cl.FC (F) (F) C1=CC=C2C (=C1) C=3C=C (Cl) C=C (Cl) C3C=C2C (O) CCN (CCCC) CCCC
Molecular Formula
C26H31Cl3F3NO
Molecular Weight
536.89
Storage Conditions
-20°C
Notes
For research use only.
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