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Halofantrine hydrochloride

Halofantrine hydrochloride (SKF-102886) is an orally administered antimalarial drug effective against drug-resistant P. falciparum and P. vivax. SKF-102886 has cardiac toxicity, inhibiting hERG and delayed rectifier potassium channel I Kr, leading to prolonged QTc and PR intervals.

Product Specifications

CAS Number

36167-63-2

Product Name Alternative

Malaria, Halofantrine Hydrochloride, Halofantrine hydrochloride, SKF 102886, SKF102886, SKF-102886, WR 171669, WR171669, WR-171669, WR-171669 hydrochloride

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (3.73 mM) ; DMSO:24 mg/mL (44.7 mM)

Smiles

Cl.FC (F) (F) C1=CC=C2C (=C1) C=3C=C (Cl) C=C (Cl) C3C=C2C (O) CCN (CCCC) CCCC

Molecular Formula

C26H31Cl3F3NO

Molecular Weight

536.89

Storage Conditions

-20°C

Notes

For research use only.

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