N-Arachidonylglycine
N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM) . Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM) . N-Arachidonylglycine also is an effective activator of endometrial cell migration[1][2].
Product Specifications
CAS Number
179113-91-8
Product Name Alternative
NA-Gly
UNSPSC
12352211
Hazard Statement
H315, H319, H336, H351
Target
Endogenous Metabolite; GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-arachidonylglycine.html
Concentration
138.30 mM * 2 mL in Ethanol
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 50 mg/mL (ultrasonic)
Smiles
O=C(O)CNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
Molecular Formula
C22H35NO3
Molecular Weight
361.52
Precautions
H315, H319, H336, H351
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GlyT2
Available Sizes
Frequently Asked Questions
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