FLT3-ITD-IN-3
FLT3-ITD-IN-3 (13v) is an orally active inhibitor of FLT3-ITD (internal tandem duplication of FLT3), which works by blocking FLT3 signaling. This inhibition leads to cell cycle arrest in the G0/G1 phase and induces apoptosis. The compound is currently employed in studies related to acute myeloid leukemia (AML) .
Product Specifications
CAS Number
3018150-80-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1C=C (C (=NN1C2=CC (Cl) =CC=C2F) C (=O) NC3=CC=C (OC=4C=CN=C (C4) NC (=O) N5CC (O) C5) C (F) =C3) C
Molecular Formula
C27H21ClF2N6O5
Molecular Weight
582.943
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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