PPARγ agonist 17
PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.
Product Specifications
CAS Number
3054652-58-0
Field of Research
Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Smiles
C[C@]12[C@@]3 (C) C ([C@]4 ([C@@] (C) (CC3) CC[C@@] (C (O) =O) (C) C4) [H]) =CC (=O) [C@@]1 ([C@]5 (C) [C@@] (CC2) (C (C) (C) [C@@H] (OC (CC6=CC (NC (COC7=C (C) C=CC (C) =C7) =O) =CC=C6) =O) CC5) [H]) [H]
Molecular Formula
C48H63NO7
Molecular Weight
766.016
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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