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Gamma-secretase modulator 6

Gamma-secretase modulator 6 (Example 50) is a gamma-secretase modulator. It inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. This compound is applicable in Alzheimer's disease research.

Product Specifications

CAS Number

1255700-88-9

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Smiles

O (C) C1=C (C=CC (NC=2N=C3C (=CC2) CN (C) C[C@H] (O3) C4=CC=CC=C4) =N1) C5=CN (C) N=C5

Molecular Formula

C25H26N6O2

Molecular Weight

442.513

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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