Hyp-dBET1
Hyp-dBET1 is a PROTAC degrader targeting BRD4, with an IC50 value of 3.4 μM in MDA-MB-231 cells. Under hypoxic conditions, Hyp-dBET1 becomes active, recruiting E3 ubiquitin ligase, and facilitates the degradation of BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable in anti-cancer research.
Product Specifications
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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