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ASK1-IN-8

ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.

Product Specifications

CAS Number

2570985-89-4

Field of Research

Cell Biology

Smiles

O=C1N (C2=NC (=CC=C2) C3=NN=CN3C (C) C) CCN1C4=CC=C (C=C4) N5CCC (C (=O) NC) CC5

Molecular Formula

C26H32N8O2

Molecular Weight

488.585

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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