ASK1-IN-8
ASK1-IN-8 (Compound 35) is an orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 value of 1.8 nM. In a mouse liver injury model induced by Acetaminophen, ASK1-IN-8 significantly reduces plasma alanine aminotransferase (ALT) levels, offering liver protection. This compound is useful for research in liver disease-related fields.
Product Specifications
CAS Number
2570985-89-4
Field of Research
Cell Biology
Smiles
O=C1N (C2=NC (=CC=C2) C3=NN=CN3C (C) C) CCN1C4=CC=C (C=C4) N5CCC (C (=O) NC) CC5
Molecular Formula
C26H32N8O2
Molecular Weight
488.585
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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