DGAT1-IN-1
Product Specifications
UNSPSC Description
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).
IC50 value: < 10 nM
Target: DGAT1 inhibitor
Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation
By Kim, Dooseop; Bok, Juhan; Shin, Sunmi
From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
Target Antigen
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/DGAT1-IN-1.html
Purity
98.0
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
OC(C[C@H]1CC[C@H](C2=CC=C(C3=CN4C=C(C(NCC5=CC=C(OC(F)(F)F)C=C5)=O)N=C4C=C3)C=C2)CC1)=O
Molecular Weight
551.56
References & Citations
[1]Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme
 , Patent: WO 2013119040 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12425/DGAT1-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12425/DGAT1-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1449779-49-0
Available Sizes
Curated Selection
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