Dirozalkib
Dirozalkib (Compound 4) is an ALK inhibitor with an IC50 of 0.9 nM. It demonstrates antiproliferative activity in cancer cells NCI-H3122, Karpas-299, and NCI-H2228, with IC50 values of 130.4, 0.71, and 15.11 nM, respectively. Dirozalkib exhibits favorable pharmacokinetic properties and a bioavailability ranging from 30% to 50%.
Product Specifications
CAS Number
1893419-37-8
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=S (=O) (C=1C=CC=CC1NC2=NC (=NC=C2Cl) NC=3C=C (C (=C4OCCOC43) C5CCNCC5) C) C (C) C
Molecular Formula
C27H32ClN5O4S
Molecular Weight
558.092
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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