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SMW139

SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimer's disease, and multiple sclerosis.

Product Specifications

CAS Number

2133010-38-3

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Smiles

O=C (NCC12CC3 (F) CC (F) (CC (F) (C3) C1) C2) C4=CC (OC) =CC=C4Cl

Molecular Formula

C19H21ClF3NO2

Molecular Weight

387.824

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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