P131
P131 is a PROTAC molecule consisting of a cereblon ligand based on Pomalidomide and IBT6A, linked via a PEG linker. P131 effectively degrades both wild-type and C481S mutant BTK with nanomolar potency.
Product Specifications
CAS Number
2360561-66-4
Field of Research
Pharmacology & Drug Discovery
Smiles
NC1=C2C (N (N=C2C3=CC=C (OC4=CC=CC=C4) C=C3) [C@H]5CN (C (=O) C6=CN (CCOCCOCCOCCNC7=C8C (C (=O) N (C8=O) C9C (=O) NC (=O) CC9) =CC=C7) N=N6) CCC5) =NC=N1
Molecular Formula
C46H48N12O9
Molecular Weight
912.948
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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