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GI-Y2

GI-Y2 is a GSDMD inhibitor that suppresses macrophage pyroptosis induced by oxidized low-density lipoprotein (ox-LDL) . In vivo, GI-Y2 dose-dependently reduces atherosclerotic plaques and decreases lesion size and fibrosis in the aortic root of ApoE-/- mice. GI-Y2 holds potential for research in pyroptosis and cardiovascular diseases, such as atherosclerosis.

Product Specifications

CAS Number

1008710-58-4

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

O=C (O) C1=CC=C (C=C1) NC2SC (=O) N (C2=O) CC3=CC=C (C=C3) C (=O) O

Molecular Formula

C18H14N2O6S

Molecular Weight

386.379

Storage Conditions

-20°C

Notes

For research use only.

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