GI-Y2
GI-Y2 is a GSDMD inhibitor that suppresses macrophage pyroptosis induced by oxidized low-density lipoprotein (ox-LDL) . In vivo, GI-Y2 dose-dependently reduces atherosclerotic plaques and decreases lesion size and fibrosis in the aortic root of ApoE-/- mice. GI-Y2 holds potential for research in pyroptosis and cardiovascular diseases, such as atherosclerosis.
Product Specifications
CAS Number
1008710-58-4
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C (O) C1=CC=C (C=C1) NC2SC (=O) N (C2=O) CC3=CC=C (C=C3) C (=O) O
Molecular Formula
C18H14N2O6S
Molecular Weight
386.379
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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