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BMS-986458

BMS-986458 is a highly selective, orally active BCL6 PROTAC degrader. It specifically targets cereblon (CRBN) and the BCL6 N-terminal BTB domain to catalyze proximity-induced BCL6 degradation. BMS-986458 is applicable for research in B-cell non-Hodgkin lymphoma.

Product Specifications

CAS Number

3005272-36-3

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

CN1C=2C (C (=N1) C3C (=O) NC (=O) CC3) =CC=C (N[C@H]4[C@H] (C) CN (CC4) C=5N=C (NC=6C=C7C (=CC6) N (C) C (=O) C7) C (Cl) =CN5) C2

Molecular Formula

C32H34ClN9O3

Molecular Weight

628.124

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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