Mal-VC-PAB-EDA-N-Ac-Calicheamicin
Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a drug-linker conjugate for ADCs, exhibiting potent antitumor activity. OncoFAP-GlyPro-MMAF is composed of the ADC toxin Calicheamicin and a linker. It is used in the synthesis of the ADC molecule PF-06647263.
Product Specifications
CAS Number
2028299-61-6
Field of Research
Stem Cell & Developmental Biology
Smiles
CCN ([C@H]1CO[C@H] (C[C@@H]1OC) O[C@@H]2[C@H] ([C@@H] ([C@H] (OC2O[C@H]3C#C/C=C\C#C[C@]\4 (CC (=O) C (=C3/C4=C\CSSC (C) (C) CCC (=O) NCCNC (=O) OCC5=CC=C (C=C5) NC (=O) [C@H] (CCCNC (=O) N) NC (=O) [C@H] (C (C) C) NC (=O) CCCCCN6C (=O) C=CC6=O) NC (=O) OC) O) C) NO[C@H]7C[C@@H] ([C@@H] ([C@H] (O7) C) SC (=O) C8=C (C (=C (C (=C8OC) OC) O[C@H]9[C@@H] ([C@@H] ([C@H] ([C@@H] (O9) C) O) OC) O) I) C) O) O) C (=O) C
Molecular Formula
C93H128IN11O31S3
Molecular Weight
2119.17
Storage Conditions
-20°C
Notes
For research use only.
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