PDHK1-IN-2
PDHK1-IN-2 (Compound 24) is an ATP-competitive dual inhibitor of pyruvate dehydrogenase kinase 1/2 (PDHK1/2), with an IC50 of 0.007 μM for PDHK1 and 0.015 μM for PDHK2. PDHK1-IN-2 has the potential to regulate immune cell metabolism and correct mitochondrial dysfunction, making it a promising candidate for research in autoimmune diseases, inflammatory conditions, and cancer.
Product Specifications
CAS Number
2870691-38-4
Field of Research
Metabolism Research
Smiles
C (C) C1 (C=2C (NC1=O) =C (NCC) C=C (F) C2) N3C[C@H] (NC (=O) C4CC5 (C4) CN (C#N) C5) CCC3
Molecular Formula
C25H33FN6O2
Molecular Weight
468.567
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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