PRMT5-MTA-IN-3
PRMT5-MTA-IN-3 (Compound P2A) is an orally active and selective inhibitor of protein arginine methyltransferase 5 (PRMT5) . It inhibits the proliferation of MTAP-deficient colorectal cancer HCT-116 cell line with an IC50 value of 5 nM. PRMT5-MTA-IN-3 holds potential for research in cancers, particularly in MTAP-deficient tumors such as colorectal cancer, non-small cell lung cancer, and pancreatic cancer.
Product Specifications
CAS Number
3028674-29-2
Field of Research
Epigenetics & Chromatin
Smiles
N (C (C (NC1=C2C (N (C) N=C2) =C (N) N=C1) =O) =O) (C) [C@H]3C=4C (=CC (C (F) (F) F) =CC4) OC3
Molecular Formula
C19H17F3N6O3
Molecular Weight
434.372
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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