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Balomenib

Balomenib is an inhibitor of the menin-MLL interaction, effectively blocking the men1-MLL4-43 interaction with an IC50 of less than 0.075 μM. It inhibits cell growth in MV4-11 (CC50 < 0.1 μM), MOLM-13 (CC50 0.1~0.5 μM), and HEK293 (CC50 < 2 μM) cells. Balomenib also exhibits antitumor activity.

Product Specifications

CAS Number

2939850-17-4

Field of Research

Epigenetics & Chromatin

Smiles

C (N1CCC2 (CN (C2) C=3C4=C (C=CC (CC (F) (F) F) =C4) N=CN3) CC1) C=5C (C) =C6C (=CC5) N (C[C@@H]7CNC (=O) CO7) C (C#N) =C6

Molecular Formula

C33H34F3N7O2

Molecular Weight

617.664

Storage Conditions

-20°C

Notes

For research use only.

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