PI4KIII beta inhibitor 5
PI4KIII beta inhibitor 5 (Compound 43) is an inhibitor of PI4KIIIβ with an IC50 of 19 nM. By inhibiting the PI3K/AKT pathway, it induces apoptosis in cancer cells, causes cell cycle arrest at the G2/M phase, and promotes autophagy. Additionally, PI4KIII beta inhibitor 5 demonstrates significant anti-tumor activity in the H446 small cell lung cancer xenograft model. This compound is applicable in cancer research studies.
Product Specifications
CAS Number
3029506-23-5
Field of Research
Metabolism Research; Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC1=NC (=C (S1) C=2C=CC (OC) =C (C2) S (=O) (=O) NCC3=CC=C (F) C=C3F) C) CCCCC
Molecular Formula
C24H27F2N3O4S2
Molecular Weight
523.616
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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