A-86929
A-86929 is a potent and selective dopamine D1 receptor agonist with a pKi of 7.3. It significantly induces rotational behavior in a 6-OHDA-induced unilateral nigral lesion rat model and improves motor function in an MPTP-induced Parkinson's disease marmoset model. Furthermore, A-86929 shows potential value in reducing cocaine-induced craving behavior in rats and reversing Haloperidol-induced cognitive deficits in rhesus monkeys. The compound is useful for researching neurological disorders.
Product Specifications
CAS Number
171961-95-8
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (CC) C1=CC=2[C@@]3 (C=4C (CC[C@]3 (NCC2S1) [H]) =CC (O) =C (O) C4) [H]
Molecular Formula
C18H21NO2S
Molecular Weight
315.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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