(Rac) -Roscovitine
(Rac) -Roscovitine ((Rac) -Seliciclib) is a selective inhibitor of cyclin-dependent kinases (CDKs) . It competes with ATP for binding at the active site of CDKs, thereby inhibiting their phosphorylation activity. This compound induces apoptosis in cancer cells and holds potential for the study of conditions like cancer, neurodegenerative diseases, heart diseases, viral and protozoal infections, glomerulonephritis, and chronic inflammation, all of which are associated with CDK dysregulation.
Product Specifications
CAS Number
186692-44-4
Field of Research
Cell Biology, Signal Transduction
Smiles
OCC (NC=1N=C (NCC=2C=CC=CC2) C=3N=CN (C3N1) C (C) C) CC
Molecular Formula
C19H26N6O
Molecular Weight
354.449
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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