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CPP12 (TFA)

CPP12 TFA is a small, amphiphilic, cyclic cell-penetrating peptide (CPP) in salt form. CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and is then efficiently released from endosomes. CPP12 TFA can be used for intracellular delivery of drugs and chemical probes[1].

Product Specifications

UNSPSC

12352209

Target

Fluorescent Dye

Type

Peptides

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cpp12-tfa.html

Purity

98.69

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C([C@H](CC1=CC=C2C=CC=CC2=C1)NC([C@H](NC([C@@H](NC3=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)=O)N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H]3CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

Molecular Formula

C68H89F12N21O17

Molecular Weight

1700.55

References & Citations

[1]Qian Z, et al. Discovery and mechanism of highly efficient cyclic cell-penetrating peptides[J]. Biochemistry, 2016, 55 (18) : 2601-2612.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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