Blixeprodil
Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 μM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 μM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.
Product Specifications
CAS Number
2881017-49-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
N (C) [C@@]1 (C (=O) CCCC1) C2=CC=C (F) C=C2
Molecular Formula
C13H16FNO
Molecular Weight
221.271
Storage Conditions
-20°C
Notes
For research use only.
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