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Thalidomide-O-PEG1-OH

Thalidomide-O-PEG1-OH is a PROTAC linker characterized by its combination of Thalidomide with O-ethyl. Thalidomide acts as a ligand for the E3 ubiquitin ligase, leading to protein ubiquitination and subsequent proteasomal degradation. Additionally, the hydroxy group serves as a versatile handle, facilitating the formation of more complex structures through various reactions.

Product Specifications

CAS Number

2416234-31-4

Field of Research

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Smiles

O=C1NC (=O) C (N2C (=O) C=3C=CC=C (OCCO) C3C2=O) CC1

Molecular Formula

C15H14N2O6

Molecular Weight

318.281

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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