SHP2-IN-36
SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2 with an IC50 of 9.0 nM, and it exhibits an IC50 of 40 nM against p-ERK. Moreover, SHP2-IN-36 demonstrates significant antitumor activity in the KYSE520 xenograft mouse model and is applicable for research in the field of antitumor studies.
Product Specifications
Field of Research
Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
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