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SIK2/3-IN-1

SIK2/3-IN-1 (Compound 7S) is an orally active and selective inhibitor of SIK2/3. It significantly inhibits tumor growth without causing weight loss in the MV4-11 AML mouse CDX model. SIK2/3-IN-1 is applicable for research in MEF2C-dependent acute myeloid leukemia.

Product Specifications

CAS Number

3038863-24-7

Field of Research

Cell Biology, Signal Transduction

Smiles

O=C1C=2C (=NC (=CC2CCN1CC (F) (F) F) C=3C=C (C=NC3N) C=4C=NN (C4) C) OC

Molecular Formula

C20H19F3N6O2

Molecular Weight

432.399

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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