(S) -PI3K-IN-2
(S) -PI3K-IN-2 is the enantiomer of PI3K-IN-2, functioning as a ΡΙ3Κβ/δ inhibitor with IC50 values of 0.198 and 0.282 μM, respectively. It can also inhibit the phosphorylation of AKT (ser473) in MDA-MB-468 cells, with an IC50 of 27 nM.
Product Specifications
CAS Number
1403458-27-4
Field of Research
Signal Transduction
Smiles
C (=O) (C1=CC (=C2C (=C1) C (=O) C=C (O2) N3CCOCC3) [C@H]4N (CCC4) C5=CC (F) =CC (F) =C5) N6CCOCC6
Molecular Formula
C28H29F2N3O5
Molecular Weight
525.544
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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