Ferroptosis inducer-7

Ferroptosisinducer-7 is an orally active and selective inducer of ferroptosis, operating through the inositol 1,4,5-trisphosphate receptor (IP3R) /ORAI calcium release-activated calcium channel protein. This compound significantly alleviates anemia, inhibits bone marrow CTL activation, and improves hematopoietic function in immune-mediated bone marrow failure. It is utilized in research on aplastic anemia.