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PAD4-IN-5

PAD4-IN-5 (Example 18) is a PAD4 inhibitor with an IC50 of ≤10 nM at 50 μM Ca2+ and 101-500 nM at 1 mM Ca2+ against human PAD4 (hPAD4) . This compound is applicable in the study of autoimmune diseases such as rheumatoid arthritis (RA) .

Product Specifications

CAS Number

3071873-52-1

Field of Research

Epigenetics & Chromatin

Smiles

CN1C (C=2N3C=4C (C2) =CC=C (N4) [C@@H] (C) NC (=O) [C@]5 ([C@] (CCCCC3) (C5) [H]) [H]) =NC=6C1=CC7=C (C6) C (=O) N (C[C@H]8COCCN8) CC7

Molecular Formula

C34H41N7O3

Molecular Weight

595.734

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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