PAD4-IN-5
PAD4-IN-5 (Example 18) is a PAD4 inhibitor with an IC50 of ≤10 nM at 50 μM Ca2+ and 101-500 nM at 1 mM Ca2+ against human PAD4 (hPAD4) . This compound is applicable in the study of autoimmune diseases such as rheumatoid arthritis (RA) .
Product Specifications
CAS Number
3071873-52-1
Field of Research
Epigenetics & Chromatin
Smiles
CN1C (C=2N3C=4C (C2) =CC=C (N4) [C@@H] (C) NC (=O) [C@]5 ([C@] (CCCCC3) (C5) [H]) [H]) =NC=6C1=CC7=C (C6) C (=O) N (C[C@H]8COCCN8) CC7
Molecular Formula
C34H41N7O3
Molecular Weight
595.734
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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