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(R) -BAY-6035

(R) -BAY-6035 is a novel inhibitor that selectively targets the methylation of MAP3K2 by SMYD3, demonstrating nanomolar potency and specificity against kinases and other protein lysine methyltransferases.

Product Specifications

CAS Number

[2283389-29-5]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-bay-6035.html

Smiles

O=C1C[C@@H](C)N(C(N2CC(C3)C3C2)=O)C4=CC=C(C(NCCC5CC5)=O)C=C4N1

Molecular Formula

C22H28N4O3

Molecular Weight

396.48

References & Citations

[1]Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA) -Based High-Throughput Screening

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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