P2Y14R antagonist 4
Compound 25l, also known as P2Y14R antagonist 4, is an orally active antagonist of the P2Y14R receptor with an IC50 of 5.6 nM. It exhibits higher binding affinity for P2Y14R compared to other PPTN receptors. P2Y14R antagonist 4 also possesses anti-inflammatory properties, reducing the release of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α) induced by LPS.
Product Specifications
CAS Number
3081687-67-1
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (O) C1=CC (=CC (=C1) C2=CC=C (C=C2) C3CCNCC3) NS (=O) (=O) CCC4=CC=C (C=C4) C (F) (F) F
Molecular Formula
C27H27F3N2O4S
Molecular Weight
532.574
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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