SARM1-IN-4
SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.
Product Specifications
CAS Number
3069378-18-0
Field of Research
Immunology & Inflammation, Neuroscience
Smiles
N (C (N ([C@@H] (C) C=1C=CN=CC1) C) =O) [C@H]2C (F) (F) COC2
Molecular Formula
C13H17F2N3O2
Molecular Weight
285.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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