SARM1-IN-4
SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.
Product Specifications
CAS Number
3069378-18-0
Field of Research
Immunology & Inflammation, Neuroscience
Smiles
N (C (N ([C@@H] (C) C=1C=CN=CC1) C) =O) [C@H]2C (F) (F) COC2
Molecular Formula
C13H17F2N3O2
Molecular Weight
285.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
227535 250 Roll (250 Panel (s) x 1 Roll)
PIC 264 RL-DIA 050-B7541 Personal Protection (PPE) Signs & Labels (Adhesive)
Sign In for Pricing
View Details GTR15084760 1 Vial
Lentiviral human FTO shRNA (UAS) - Lentiviral human FTO shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details OR1054785 250 mg
6- (3-Chlorophenyl) -2-oxo-1,2-dihydropyridine-3-carbonitrile
Sign In for Pricing
View Details 
abx156918-01 96 Tests
Human Adrenergic Receptor Beta 3 (ADRB3) ELISA Kit
Sign In for Pricing
View Details abx156918-02 5x 96 Tests
Human Adrenergic Receptor Beta 3 (ADRB3) ELISA Kit
Sign In for Pricing
View Details abx156918-03 10x 96 Tests
Human Adrenergic Receptor Beta 3 (ADRB3) ELISA Kit
Sign In for Pricing
View Details