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TCIP3

TCIP3 is a bivalent molecular glue (molecular glue) that can simultaneously bind to both p300/CBP and BCL6. It redirects p300 and CBP to activate programmed cell death genes, which are typically repressed by the oncogenic driver BCL6. TCIP3 is useful for studying diffuse large B-cell lymphoma (DLBCL) and is not toxic to untransformed tonsil lymphocytes or fibroblasts.

Product Specifications

CAS Number

3067681-36-8

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

O=C (NC) N1CC=2C (=NN (C2CC1) C3CCN (C (=O) CCN4CCN (C (=O) C5CCN (C6=NC=C (Cl) C (=N6) NC=7C=C (OC) C8=C (C=C (OCC (=O) NC) C (=O) N8C) C7) CC5) CC4) CC3) N9C=%10C=C (C (=CC%10CCC9) C=%11C=NN (C%11) C) C (F) F

Molecular Formula

C58H71ClF2N16O7

Molecular Weight

1177.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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