TCIP3
TCIP3 is a bivalent molecular glue (molecular glue) that can simultaneously bind to both p300/CBP and BCL6. It redirects p300 and CBP to activate programmed cell death genes, which are typically repressed by the oncogenic driver BCL6. TCIP3 is useful for studying diffuse large B-cell lymphoma (DLBCL) and is not toxic to untransformed tonsil lymphocytes or fibroblasts.
Product Specifications
CAS Number
3067681-36-8
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C (NC) N1CC=2C (=NN (C2CC1) C3CCN (C (=O) CCN4CCN (C (=O) C5CCN (C6=NC=C (Cl) C (=N6) NC=7C=C (OC) C8=C (C=C (OCC (=O) NC) C (=O) N8C) C7) CC5) CC4) CC3) N9C=%10C=C (C (=CC%10CCC9) C=%11C=NN (C%11) C) C (F) F
Molecular Formula
C58H71ClF2N16O7
Molecular Weight
1177.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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