HW161023
HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.
Product Specifications
CAS Number
2920698-73-1
Field of Research
Neuroscience
Smiles
O (C[C@@] (CC (C) C) (C) N) C=1N2C (C (=CC1) C=3C=C (C (F) F) N=CC3) =NC=C2
Molecular Formula
C20H24F2N4O
Molecular Weight
374.428
Storage Conditions
-20°C
Notes
For research use only.
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