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HW161023

HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.

Product Specifications

CAS Number

2920698-73-1

Field of Research

Neuroscience

Smiles

O (C[C@@] (CC (C) C) (C) N) C=1N2C (C (=CC1) C=3C=C (C (F) F) N=CC3) =NC=C2

Molecular Formula

C20H24F2N4O

Molecular Weight

374.428

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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