P38α inhibitor 6
P38α inhibitor6 (compound 19) is a p38α inhibitor with an IC50 value of 0.68 μM. It induces apoptosis, arrests the cell cycle in the G0 and G2/M phases, reduces TNF-α concentration, upregulates the expression of the tumor suppressor gene p53, increases the Bax/BCL-2 ratio, and activates caspase3/7.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
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