SDH-IN-25
SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.
Product Specifications
CAS Number
3052432-15-9
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry, Signal Transduction
Smiles
O=C1OC (C=2C=C (Cl) C=C (Cl) C2OCC (=O) NNC3=CC=C (Br) C=C3) CC1=C
Molecular Formula
C19H15BrCl2N2O4
Molecular Weight
486.143
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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