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PROTAC KDM4 degrader-1

PROTACKDM4 degrader-1 (Compound 11) is a proteolysis-targeting chimera (PROTAC) degrader specifically designed for KDM4. It effectively degrades KDM4A-C while sparing KDM4D. In esophageal cancer cells, PROTACKDM4 degrader-1 demonstrates strong antiproliferative activity, inducing apoptosis and cell cycle arrest, and inhibits lysine demethylation of histone H3.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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