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RIPK1-IN-29

RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor with an IC50 of 6.9 nM. It exhibits anti-necroptotic apoptosis activity by inhibiting RIPK1. In a TNF-α induced inflammatory in vivo model, a 10 mg/kg dose of RIPK1-IN-29 can protect mice from hypothermia and death. This compound is suitable for research in the field of inflammatory diseases.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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