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BTR2004

BTR2004 is a selective PROTAC degrader targeting the BET family (BRD2/3/4) proteins. It facilitates the formation of a ternary complex with BRD proteins and KLHL20, leading to ubiquitination and proteasomal degradation via the UPS pathway. BTR2004 shows potential for research in PC3 prostate cancer and MDA-MB-231 breast cancer cell lines.

Product Specifications

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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