CB039
CB039 is a selective degrader targeting RBM39 (RNA binding motif protein 39) . It facilitates the formation of a ternary complex between RBM39 and the E3 ubiquitin ligase CUL4-DCAF15, resulting in the proteasomal degradation of RBM39. CB039 holds promise for research into cancers dependent on RBM39, such as acute myeloid leukemia (AML) and ovarian cancer.
Product Specifications
CAS Number
3056259-55-0
Field of Research
Pharmacology & Drug Discovery
Smiles
N (S (=O) (=O) C1=CC (NC (C (=O) N2[C@@H] (CO) CCC2) =O) =CC=C1) C3=C4C (C (C#N) =CN4) =C (C) C=C3
Molecular Formula
C23H23N5O5S
Molecular Weight
481.524
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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